L-Malic acid

Tsanangudzo Pfupi:

Product Name:L-Malic acid

Mashoko anoreva zvakafanana:L-(-)-Malic acid, CP;Butanedioic acid, 2-hydroxy-, (2S)-;pinguosuan;Butanedioicacid,hydroxy-,(S)-;hydroxy-,(S)-Butanedioicacid;l-(ii) -malicacid;L-Gydroxybutanedioicacid;L-Mailcacid

CAS:97-67-6

MF:C4H6O5

MW:134.09

EINECS:202-601-5

Product Categories:Zvekudyara;Aliphatics;MalicAcidSeries;Carboxylic Acids (Chiral);Chiral chemicals;Chiral Reagents;Zvokudya & ZVOKUDYA ZVOKUWEDZERA;Chiral Building Blocks;Kugadzirisa Mabhesi;Optical Resolution;Synthetic Organic Chemistry;Chikafu chekuwedzera uye acidulant;Imidazoles Acidulant;Imidazoles Acids bc0001

Mol Faira:97-67-6.mol

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Malic acid Chemical Properties

Melting point	101-103 °C (lit.)
alpha	-2 º (c=8.5, H2O)
Boiling point	167.16°C (yakaomarara fungidziro)
density	1.60
mhute pressure	0Pa pa25 ℃
refractive index	-6.5 ° (C=10, Acetone)
FEMA	2655 \|L-MALIC ACID
Fp	220 °C
kuchengetedza temp.	Chengetedza pasi pe +30°C.
solubility	H₂O: 0.5 M pa20 °C, yakajeka, isina ruvara
form	Upfu
color	Chena
Specific Gravity	1.595 (20/4℃)
PH	2.2 (10g/l, H2O, 20℃)
pka	(1) 3.46, (2) 5.10(pa25℃)
optical chiitiko	[α]20/D 30±2°, c = 5.5% mupyridine
Mvura Solubility	soluble
Merck	14,5707
Nhamba yeJECFA	619
BRN	1723541
InChIKey	BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP	-1.68
CAS DataBase Reference	97-67-6(CAS DataBase Reference)
NIST Chemistry Reference	Butanedioic acid, hydroxy-, (s)-(97-67-6)
EPA Substance Registry System	Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
RTECS	ON7175000
TSCA	Ehe
HS Code	29181980

Malic acid Kushandisa uye Synthesis

Tsanangudzo	L-Malic acid inenge isina kunhuhwirira (dzimwe nguva kunhuhwirira, acrid kunhuhwirira) ine tart, acidic kuravira.Hazvina pungent.Inogona kugadzirirwa ne hydration ye maleic acid;nekuviriswa kubva kushuga.
Chemical Properties	L-Malic asidhi inenge isinganhuhwi (dzimwe nguva kufenda, kunhuhwirira).Mushonga uyu une tart, acidic, nonpungent kuravira.
Chemical Properties	mhinduro yakajeka isina ruvara
Chiitiko	Inowanikwa mumaple sap, apuro, melon, papaya, doro, waini yemazambiringa, cocoa, sake, kiwifruit uye chicory mudzi.
Uses	L-Malic acid inoshandiswa sechikafu chekuwedzera, Selective α-amino inodzivirira reagent yeamino acid derivatives.Yakasiyana-siyana synthon yekugadzirira kwechiral compounds kusanganisira κ-opioid receptor agonists, 1α, 25-dihydroxyvitamin D3 analogue, uye phoslactomycin B.
Uses	Iyo inowanzoitika isomeri ndiyo L-fomu yakawanikwa mumaapuro nemimwe michero yakawanda nemiti.Kusarudza α-amino inodzivirira reagent yeamino acid derivatives.Yakasiyana-siyana synthon yekugadzirira kwechiral compounds kusanganisira κ-opioid rece
Uses	Pakati pemakemikari synthesis.Chelating uye buffering agent.Flavoring agent, flavour enhancer uye acidulant muzvokudya.
Tsanangudzo	ChEBI: An optically inoshanda fomu ye malic acid ine (S) -kugadzirisa.
Kugadzirira	L-Malic acid inogona kugadzirirwa ne hydration ye maleic acid;nekuvirisa kubva mushuga.
General Description	L-Malic acid is organic acid inowanikwa muwaini.Inoita basa rakakosha muwaini microbiological kugadzikana.
Biochem/physiol Zviito	L-Malic acid chikamu chesero metabolism.Kushandiswa kwayo kunozivikanwa mumishonga.Inobatsira mukurapa kwehepatic malfunctioning, inoshanda kurwisa hyper-ammonemia.Inoshandiswa sechikamu cheamino acid infusion.L-Malic acid inoshandawo se nanomedicine mukurapa kwehuropi neurological kusagadzikana.A TCA (Krebs cycle) yepakati uye shamwari mune malic acid aspartate shuttle.
Kuchenesa Nzira	Crystallize S-malic acid (marasha) kubva ethyl acetate/pet ether (b 55-56o), kuchengetedza tembiricha iri pasi pe65o.Kana kuti kuinyungudutsa nekudzoreredza muzvikamu gumi neshanu zveanhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, kasingaperi kusvika kunogara kunyungudika.[Beilstein 3 IV 1123.]