Zvigadzirwa
Dicyclheyexylcarbodiimide; Cas No.: 538-75-0
Synonyms: DCCD; DicycloRecylcarbodiimide
Chemical midziyo ye dicyclhexeclarbodiimide
● Chitarisiko / Ruvara: Ruvara rusina ruvara
● Vapor Kumanikidzwa: 1.044-1.15pa pa 20-25 ℃
● Rolling Point: 34-35 ° C (lit.)
● Refractive Index: N20 / D 1.48
● Kubirirwa Point: 277 ° C at 760 mmhg
● Flash Pfungwa: 113.1 ° C
● PSA:24.72000
● Density: 1.06 g / cm3
● logp: 3.82570
● Kuchengetedza temp.Iksore kuRT.
● Sensitive.4misture unonzwa
● Solubility.4methylene chloride: 0.1 g / ml, yakajeka, isina ruvara
● Solublity Mvura.Ereittion
● XLOGP3: 4.7
● Hydrogen Bond anopa kuverenga: 0
● Hydrogen Bond AngelCon Kuverenga: 2
● Kuverengera Bond Count: 2
● Zvakakodzera: 206.178298710
● Anorema Atomu Kuverenga: 15
● kuoma: 201
● Transport dot Label: chepfu
Ruzivo rwekufa
● pikicha (s):
T,
Xn
● Hazard Codes: t, xn, t +
● Zvirevo: 23/14 / 25-34-40-43-41-36 / 38-01-2-36 / 38-10-61-27-27-20 / 22
● Safety Statements:26-36/37/39-45-41-24-37/39-24/25-36-16-53-28
Zvinoshanda
Makirasi emakemikari:Nitrogen Compounds -> Dzimwe Nitrogen Compounds
Canonical kunyemwerera:C1CCC (CC1) N = C = NC2CCCC2
Tsanangudzo:Dicydohexyl Carbodiimide anoshandiswa mune yePeptide Chemistry seyakaodzokorora. Izvo zvese zviri zviviri kutsamwisa uye sensitizer, uye zvakakonzera kusangana neDermatitis mumafemants uye makemikari.
Inoshandisa:Mune synthesis yemapipi. Ichi chigadzirwa chinonyanya kushandiswa muAmIikacin, Glutatione dehddrts, pamwe neSynthesis yeAcid Andhydride, Aldehyde, Ketone, Osocynate; Kana ichishandiswa sekushomeka kwemhepo yekubvisa mumiririri, inobata kuna DicyclheyexclExELEA kuburikidza nepfupi-nguva yekuita pasi peyakajairika tembiricha. Ichi chigadzirwa chinogona zvakare kushandiswa mune synthesis yePeptide uye nucleic acid. Zviri nyore kushandisa ichi chigadzirwa kuti uite neyakaomeswa yeako carboxy uye amino-boka kuita peptide. Ichi chigadzirwa chinoshandiswa zvakanyanya mune zvekurapa, hutano, kugadzira uye zvigadzirwa zvezvisungo, uye mamwe minda yekudyidzana. N, n'-dicyclenixylcarbodiimiide its a carbodiimiide inoshandiswa kune vaviri vaviri ACDs N, n'-dicycleclenixylcarbodiimide inoshandiswa seyenzi yemhepo yekugadzirira mafambiro, Kotoni, NationalSexials uye nekukasira kwechipiri callols. DicyclokoRoxylcarbodiimide inoshandiswa seyenzhenti yekushomeka pamhepo tembiricha mushure menguva pfupi yekuita nguva, mushure mekuita chigadzirwa cheDicyclEHELEKELEXELEA. Iyo chigadzirwa idiki diki solubility mune organic solvent, zvekuti nyore kupatsanurwa kwechigadzirwa chezvigadzirwa.
Tsanangudzo yeruzivo
Dicyclheyexylcarbodiimide (DCCC) inoshandiswa inowanzo shandiswa mune organic synthesis. Iyo chena yakasimba iyo isingaoneke mumvura uye inonyudza mumhando ye organc sols yakadai seEthyl acetate uye dichlomethane.
DCC inonyanya kushandiswa semumiriri wePeptide synthesis uye zvimwe zviitiko zvinosanganisira kuumbwa kwezvinhu zvisungo zveMidide. Iyo inosimudzira iyo curnensation ye carboxyylic acids ine maAppines, inotungamira kugadzirwa kwemamondi. Inoita izvi nekumisa iyo carboxylic acid Boka uye kufambisa iyo nucleophilic kurwiswa kweiyo Amine pane yakagadziriswa carbonfonyl kabhoni.
Pamusoro pePeptide Synthesis, DCC inoshandiswawo mune dzakasiyana siyana organic maitiro, sekusimbisa uye kushamwaridzana. Inogona kushandiswa kuumba geners kubva kuCarboxyllic Acids uye Accalhols, uye kushandura Carboxylic acid Derivatives (senge acid chlorides, acid andydrides, uye akaomesesa esters) mumafambi.
DCC inozivikanwa nekunyanyisa kugona kwekusimudzira maAdide chisungo chekuumbwa uye nekuenderana kwayo nemapoka akawanda akasiyana emapoka anoshanda. Nekudaro, inofungidzirwa zvakare kuve yakanyorova-inonamira uye inogona kuora nyore nyore pakuratidzwa nemvura kana kunyorova kwakanyanya. Naizvozvo, inowanzo kubatwa uye inochengeterwa pasi pemamiriro ezvinhu eshinda.
Izvo zvakakosha kutora manyawi ekudzivirira kana uchishanda neDCC, sezvazvinogona kutsamwisa paganda, maziso, uye maitiro ekufema. Kuchengeterwa kwakakodzera uye michina yekudzivirira inofanira kushandiswa panguva yekubata kwayo.
Application
Dicyclhexylarbodiimide (DCC) anowana akasiyana mashandisirwo ejekisirwo synicesis, kunyanya mumunda wePeptide Chemistry. Heano mashoma mashoma ekushandisa mafcc:
Peptide Synthesis:DCC inowanzoshandiswa semumiriri wepamhepo muPeptide synthesis kuti ubatane amino acids pamwe chete uye fomu emagetsi zvisungo. Iyo inosimudzira maitiro ekuburitsa pakati peboka reCarboxyl yeimwe amino acid uye iyo Ambino boka reumwe, rinotungamira kuumbwa kwezvinhu zvepachibhoni.
Ekuzivisa maitiro:DCC inogona kushandiswa kushandura carboxylic acids nekuzviita necalhopls. Pamberi peDCC, iyo carboxylic acid inoitwa, ichibvumira kurwiswa kwenyuji nedoro kuti riite ester. Kuita uku kunobatsira mune synthesis yesters kune dzakasiyana siyana application.
Endeity maitiro:DCC inogona kufambisa iyo kambani ye carboxyllic acids, acid chlorides, acid anydrides, uye akaomesesa esters. Inotadza kuita pakati pe carboxylic acid inobviswa uye ambine kuti iite chisungo chipi. Iyi application inowana utility mune synthesis yemamondioni, izvo zvakakosha mumisangano dzakasiyana siyana uye yemakemikari.
Ugi kuita:DCC inogona kushandiswa muUgia reaction, multicompononoction yekuita inosanganisira kudzora kweiyo ambenisi, iyo isocyanide, karbonyl carpound, uye acid. DCC inobatsira mukuvandudza iyo carboxyl boka recid yecid, ichibvumira kuti uite neAmine uye gadzira chisungo cheshuwa.
Zvinodhaka synthesis:DCC inowanzo shanda muindasitiri yemishonga yeiyo synthesis yevanodhaka uye vanoshanda mishonga yemishonga (APSI). Kushandiswa kwayo muPeptide synthesis, maAptions, uye kumwe kushandurwa kwakakosha kunoita kuti ive yakakosha mukuwanikwa kwezvinodhaka uye maitiro ekuvandudza.
Izvo zvakakosha kutarisa kuti DCC ine zvimwe zvinoshandiswa mu organic Synthesis, kusanganisira kuumbwa kweUreas, mabhokisi, uye hydrazides. Kuwedzera kwayo uye kuwirirana nemapoka akasiyana-siyana anoshanda anoita chishandiso chakakosha mubhokisi rezvekushandisa kwemakemikari echiSynthetic.
