Zvigadzirwa
Di-tert-butyl dicarbonate; Casha:: 2424-9-5-5
Synonyms.
Chemical gadzi ye di-tert-butyl dicarbonate
● Chitarisiko / Ruvara: White Kuti Ubike-White Microcrystalline poda
● Vapor Pressure: 0.7mmhg pa 25 ° C
● Rolling Pfungwa: 22-24 ° C
● Refractive Index: 1.4090
● Boint poir: 235.8 ° C at 760 mmhg
● Flash Pfungwa: 103.7 ° C
● PSA:61.83000
● Density: 1.054 g / cm3
● logp: 2.87320
● Kuchengetedza Temp.:26 OLOC
● Sensitive.4misture unonzwa
● Solubity mvura.
● XLOGP3: 2.7
● Hydrogen Bond anopa kuverenga: 0
● Hydrogen Bond Anogamuchira Kuverenga: 5
● Kutyisa Bond Count: 6
● Zvakakodzera: 218.11542367
● Anorema Atomu Kuverenga: 15
● kuoma: 218
Ruzivo rwekufa
● pikicha (s):
T, t +,
F, F +,
Xi
● Hazard Codes: t +, t, f, xi, f +
● Zvirevo: 11-19-26-36 / 37 / 38-43-10
● Zvirevo Zvekuchengetedza: 16-26-28-36 / 37-45-7-7 / 9-37 / 39-24-36 / 37/29-33
Zvinoshanda
Makirasi emakemikari:Mamwe makirasi -> esters, zvimwe
Canonical kunyemwerera:Cc (c) (c) oc (= o) oc (= o) oc (c) (c) c
Inoshandisa:Di-tert-butyl dicarbonate (boc2o) ndeye yakashandiswa zvakanyanya nekushandiswa kwekusuma mapoka ekudzivirira muPeptide synthesis. Inotora basa rakakosha mukugadzirira kwe6-acetyl-1,2,3,4-tetrahydropyridine nekuita ne 2-piperidone. Inoshanda seboka rekuchengetedza rinoshandiswa mune yakasimba chikamu chePettesis.
Tsanangudzo yeruzivo
Di-tert-butyl dicarbonateiri reagent inoshandiswa mu organic synthesis. Inozivikanwawo seT-Boc Anhydride kana Boc Anhydride. Zvinowanzoshandiswa kuchengetedza ambure anoshanda mapoka panguva yemakemikari maitiro. Di-tert-butyl dicarbonate inobata nema amines yekuumba carbamate inobva, ichivapa dziviriro kwenguva pfupi yeboka emain. Kamwe kuitwa kwaunoda kuzadzisa, boka reCarbamate rinogona kubviswa nyore nyore nekurapwa neAcid, kupa iyo yekutanga ambure kushanda. Ichi chiitiko chinoshanda chekusarudza kusarudza mamwe mapoka anoshanda mumorekuru emamorekuru.
Application
Pamusoro pekuchengetedza Amine mapoka, di-tert-butyl dicarbonate ane mamwe mabasa akasiyana mu orghic synthesis:
Dziviriro yemapoka eHydroxyl:Di-tert-butyl dicarbonate inogona kuita necalhopls kuumba carbonates, ichidzivirira iyo hydroxyl boka. Boka reCarbonate rinogona kubviswa richishandisa mamiriro akakodzera, achibvumira kusarudzika kwekugadziridzwa kwemamwe mapoka anoshanda.
Carbonylationlation:Di-tert-butyl dicarbonate inogona kushandiswa seinobva kabhoni monoxide muCarbonationlationlationlation. Inobata nemidziyo yakadai senge mainini, masaga, uye makumbo kuti ugadzire zvigadzirwa zvekariniti.
Kugadzirira kweAcid chlorides:Kuita Di-tert-butyl dicarbonate neTilayl Acid chlorides reattile reagents inoshandiswa mune dzakasiyana siyana dze synthetic shanduko.
Solid-Phase Peptide Synthesis:Di-tert-butyl dicarbonate inowanzoshandiswa mukudzivirira uye deprotection matanho muSolid-Phapside synthesis. Izvo zvinoshandiswa kuchengetedza amino acids panguva yekuwedzera kwekuwedzera uye kubvisa kuchengetedza mapoka kufumura maAbino mapoka ezviitiko zvakazotevera.
Polymerization Rections:Di-tert-butyl dicarbonate inogona kuita seketani kuendesa mumiriri muPolymerization maitiro. Zvinogona kuita nekukura chiketani, kudzima kukura kwavo kana kugadzira nzvimbo itsva dzekutevera.
Iyi ingori mienzaniso mishoma yezvakawanda zvekushandisa zveDi-tert-butyl dicarbonate mu orghic synthesis. Yayo inoshamisa uye yekureruka yekushandisa inoita kuti ive yakakosha pakushandurwa kwemakemikari akasiyana.
