Products
2,4-Diamino-6-hydroxypyrimidine
Hydroxypyrimidine Chemical Properties
| Melting point | 285-286 °C (December) (lit.) |
| Boiling point | 234.22°C (yakaomarara fungidziro) |
| density | 1.3659 (yakaomarara fungidziro) |
| refractive index | 1.7990 (kufungidzira) |
| kuchengetedza temp. | Ramba uri munzvimbo ine rima, Inert atmosphere, Tembiricha yemumba |
| solubility | DMSO (Zvishoma), Methanol (Zvishoma) |
| pka | 10.61±0.50(Zvakafanotaurwa) |
| form | Yakanaka Crystalline Powder |
| color | Muchena kune kirimu |
| Sensitive | Chiedza Sensitive |
| Merck | 14,2981 |
| BRN | 125006 |
| InChIKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| CAS DataBase Reference | 56-06-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 4(1H)-pyrimidinone, 2,6-diamino-(56-06-4) |
| EPA Substance Registry System | 2,6-Diamino-4(1H)-pyrimidinone (56-06-4) |
Hydroxypyrimidine Chigadzirwa Tsananguro
2,4-Diamino-6-hydroxypyrimidine ikemikari yemakemikari ine molecular formula C4H6N4O.Iyo organic compound ndeyemhuri yepyrimidine.Mushonga wacho une pyrimidine ring structure, mapoka maviri emamino (NH2) akabatanidzwa pa 2-position uye 4-position, uye boka re hydroxyl (OH) rakabatanidzwa pa 6-nzvimbo.Chimiro chemakemikari chinogona kuratidzwa se:ammonia ||H--C--C--C--N--C--C--NH2 || oh 2,4-Diamino-6-hydroxypyrimidine ine maitiro akasiyana-siyana muindasitiri yemishonga.Iyo yakakosha yepakati mukugadzirwa kwemishonga yakawanda, kusanganisira antiviral uye antitumor zvinodhaka.Inoshandiswawo kugadzira akati wandei nucleotide analogs anoshandiswa mukutsvaga kwemishonga.
Mukuwedzera kune kushandiswa kwemishonga, 2,4-diamino-6-hydroxypyrimidine inoshandiswawo sechinhu chinoshandiswa mune agrochemicals.Icho chinhu chakakosha mukubatanidzwa kwezvinomera kukura zvinodzora uye fungicides.Zvinonyanya kukosha kutevera zvakakodzera kuchengetedza protocol paunenge uchishandisa 2,4-diamino-6-hydroxypyrimidine.Sezvo ichirondedzerwa sechinhu chinogumbura kemikari, inofanira kubatwa nekuchenjerera uye midziyo yekudzivirira yakakwana inofanira kupfekwa kudzivirira kubata zvakananga.
Muchidimbu, 2,4-diamino-6-hydroxypyrimidine is organic compound ine maapplication muminda yemishonga neyekurima.Chimiro chayo chemakemikari chinoita kuti ive yakakosha seyepakati mukugadzirwa kwemishonga uye zvinomera zvinokura.
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-24/25-36-26 |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| TSCA | Ehe |
| HS Code | 29335995 |
Hydroxypyrimidine Kushandiswa uye Synthesis
| Tsanangudzo | 2,4-Diamino-6-hydroxypyrimidine (DAHP) inosarudza, chaiyo inhibitor yeGTP cyclohydrolase I, chiyero chekudzikisa danho re de novo pterin synthesis.Mumasero eHUVEC, iyo IC50nokuda kwekudzivisa BH4biosynthesis inenge 0.3 mmM.DAHP inogona kushandiswa kunyatsovharisa NO kugadzirwa mune akati wandei masero. |
| Chemical Properties | White Solid |
| Uses | 2,4-Diamino-6-hydroxypyrimidine (DAHP) inosarudza, chaiyo inhibitor yeGTP cyclohydrolase I, chiyero chekudzikisa danho re de novo pterin synthesis.Mumasero eHUVEC, iyo IC50 yekuvharisa BH4 biosynthesis ingangoita 0.3 mM.DAHP inogona kushandiswa kunyatsovharisa NO kugadzirwa mumasero akati wandei.[Cayman Chemical] |
| Uses | Inomira pakutanga kweiyo enzyme-catalyzed cascade inotanga neiyi minomwe-carbon carbohydrate uye inopera neanonhuwirira amino acids phenylalanine, tyrosine, uye tryptophan. |
| Uses | 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) isanganiswa inobatsira mukugadzirwa kwehupenyu. |
| Kuchenesa Nzira | Inodzokorora kubva kuH2O.[Beilstein 25 III/IV 3642.] |
