● Chitarisiko/Ruvara:chichena chakasimba
● Mutsipa Wemvura: 0.00232mmHg pa25°C
● Panonyungudika:285-286 °C (dec.)(lit.)
● Refractive Index:1.7990 (kufungidzira)
● Boiling Point:288.5 °C pa760 mmHg
● PKA:10.61±0.50(Zvakafanotaurwa)
● Flash Point:128.3 °C
● PSA: 98.05000
● Density:1.84 g/cm3
● LogP: 0.50900
● Kupisa Kwekuchengetedza.: Desiccate pa +4°C
● Sensitive.: Chiedza Chinonzwa
● Solubility.:DMSO (Zvishoma), Methanol (Zvishoma)
99% * data kubva kune mbishi vatengesi
2,4-Diamino-6-hydroxypyrimidine * data kubva kune reagent suppliers
● Mapikicha:Xi
● Mitemo Yenjodzi:Xi
● Mashoko:36/37/38
● Mashoko Okuchengetedza: 22-24/25-36-26
● Tsanangudzo: 2,4-Diamino-6-hydroxypyrimidine (DAHP) is selective, specific inhibitor yeGTP cyclohydrolase I, chiyero chekugadzirisa danho re de novo pterin synthesis.Mumasero eHUVEC, iyo IC50 yekuvharisa BH4 biosynthesis ingangoita 0.3 mM.DAHP inogona kushandiswa kunyatsovharisa NO kugadzirwa mune akati wandei masero.
● Zvishandiso: 2,4-Diamino-6-hydroxypyrimidine (DAHP) inosarudza, chaiyo inhibitor yeGTP cyclohydrolase I, chiyero chekugadzirisa danho re de novo pterin synthesis.Mumasero eHUVEC, iyo IC50 yekuvharisa BH4 biosynthesis ingangoita 0.3 mM.DAHP inogona kushandiswa kunyatsovharisa NO kugadzirwa mumasero akati wandei.[Cayman Chemical] Inomira panotangira enzyme-catalyzed cascade inotanga neiyi seven-carbon carbohydrates uye inopera nekunhuhwirira amino acids phenylalanine, tyrosine, uye tryptophan. 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) musanganiswa unobatsira mune organic synthesis.
2,4-Diamino-6-hydroxypyrimidine ikemikari yemakemikari ine molecular formula C4H6N4O.Inowanzoshandiswa sepakati mukugadzirwa kwemishonga yakasiyana-siyana, kusanganisira mishonga yemishonga uye dhayi.Mushonga wacho une pyrimidine ring structure inoumbwa nemapoka maviri emamino (NH2) uye rimwe boka re hydroxyl (OH) rakabatanidzwa kune akasiyana maatomu e carbon.Ichi chimiro chinoita kuti ive chivako chekuvaka chakasiyana-siyana chekugadzirwa kwemamwe mamorekuru akaoma.Iine maitiro akawanda mumhizha yemishonga, kunyanya mukugadzirwa kwemishonga inorwisa kenza uye maantibioti.