Zvigadzirwa
2,4-diamino-6-hydroxypyrimidine; Casha Kwete: 56-06-4
Synonyms: 4 (1h) -Pyrimidinone, 2,6-diamino- (8000) 2,6-diamino-4-hydroxypyrimidine; 2,6-diamino-4-pyrimilinepyrimidin-4-one; 2-one)-2,6-aminoisocytosine; 6-hydroxy-2,4-pyrimidinedineamine; NSC 44914; NSC 680818; NSC9302;
Chemical Proves ye2,4-diamino-6-hydroxypyrimidine
● Chitarisiko / Ruvara: White Solid
● Vapor Kumanikidza: 0.00232mmhg pa25 ° C
● Rolling Point: 285-286 ° C (Dec.) (Lit.)
● Refractive Index: 1.7990 (fungidzira)
● Kubikwa Point: 288.5 ° C at 760 mmhg
● Pka: 10.61 × 0.50 (yakafanotaura)
● Flash Pfungwa: 128.3 ° C
● Psa: 98.05000
● Density: 1.84 g / cm3
● logp: 0.50900
● Kuchengetedza temp.:desiccate at + 4 ° C
● Sensitive.:light inotyisa
● Solubility.:dmso (zvishoma), methanol (zvishoma)
Ruzivo rwekufa
● pikicha (s):
Xi
● Hazard Codes: Xi
● Zvirevo: 36/37/38
● Zvirevo Zvekuchengetedza: 22-24 / 25-36-26
Zvinoshanda
● Tsananguro: 2,4-diamino-6-hydroxypyrimidine (Dahp) inyanzvi, yakatwasuka yeGTP cyclohydrolase ini, iyo mwero kudzora nhanho for de novo pterin synthesis. MuHuve cles, iyo Ic50 yeChisimba yeBH4 Biosynthesis inenge 0.3 mm. DAHP inogona kushandiswa kunyatsovharira kuvhara hapana kugadzirwa mumhando dzinoverengeka.
● Kushandisa: 2,4-diamino-6-hydroxypyrimidine (DAHP) inhibitor yeGTP cyclase ini, iyo mwero kudzora nhanho ye de novo pterin synthesis. MuHuve cles, iyo Ic50 yeChisimba yeBH4 Biosynthesis inenge 0.3 mm. DAHP inogona kushandiswa kunyatsovharira hapana kugadzirwa mumhando dzinoverengeka dzechitokisi. compound inobatsira mu organic synthesis.
2,4-diamino-6-hydroxypyrimidine ndeyemakemikari yakaenzana neiyo molecular formula c4h6n4o. Izvo zvinowanzoshandiswa sepakati mune synthesis dzakasiyana siyana, kusanganisira zvinodhaka zvemishonga uye dutu Ichi chimiro chinoita kuti ive nzvimbo yekuvhara kwakawanda kweiyo synthesis yemamolekholies.2,4-hydroxypypyrimidine inogona kuwanikwa nedzidzo dzakasiyana-siyana dzekudyidzana, kusanganisira kuita kweCyanamili naUrea. Iyo ine yakati wandei indasitiri yemishonga yemishonga, kunyanya mune synthesis madhiragi uye mishonga inorwisa mabhakitiriya.orellpypyrimidine inokonzeresa mari yemakemikari akasiyana nemishonga yemishonga.
Tsanangudzo yeruzivo
2,4-diamino-6-hydroxypyrimidine ndeyemakemikari yakaenzana neiyo molecular formula c4h6n4o. Iyo organic compind iri yemhuri yePyrimidine. Iyo compound ine pyrimidine mhete, mapoka maviri emapoka (NH2) akabatana pa2-chinzvimbo uye 4-chinzvimbo, uye ohdroxyl boka (OH) rakabatana ne6-chinzvimbo. Chemakemi Chimiro chinogona kutaurwa se: Ammonia | | H - C - C - C - n - C - C - NH2 | | Ah 2,4-diamino-6-hydroxypyrimidine ine akasiyana mashandisirwo eindasitiri yemishonga. Iyo yakakosha yepakati mune synthesis yezvinodhaka zvakawanda, kusanganisira zvinodhaka uye Antitumor zvinodhaka. Iyo inoshandiswawo kugadzira akati wandei nyukireki analogs inoshandiswa mukutsvaga kwemishonga.
Kuwedzera kune mishonga yemishonga, 2,4-diamino-6-hydroxypyprimidine inoshandiswawo sechinhu chinoshandiswa muAgrochemicals. Icho chakakosha chinongedzo mune synthesis yezvirimwa kukura kwemadzitateguru uye fungicides. Izvo zvakakosha kuti utevedze protocol yakakwana kana uchishandisa 2,4-diamino-6-hydroxypyrimidine. Sezvo ichinge yatsakatiswa semakemikari akatsamwiswa, inofanira kubatwa nehanya uye yakakwana yekudzivirira yemunhu midziyo inofanira kupfekwa kuti arege kusangana zvakananga.
Mune pfupiso, 2,4-diamino-6-hydroxypyrimidine inzvimbo yeiyo organic ine apppound ine apppounds mune mishonga mumishonga yemishonga uye yeminda yekurima. Chimiro charo chemakemikari chinoita kuti ibatsire seyakawirirana mune synthesis yemishonga yemishonga uye chirimwa kukura kwemadzitateguru.
